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Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer
Liver cancer is the second-most frequent cause of cancer death in the world and is highly treatment resistant. We reported previously that inhibition of neddylation pathway with specific NAE inhibitor MLN4924, suppressed the malignant phenotypes of liver cancer. However, during the process, MLN4924...
Autores principales: | Chen, Ping, Hu, Tao, Liang, Yupei, Jiang, Yanan, Pan, Yongfu, Li, Chunjie, Zhang, Ping, Wei, Dongping, Li, Pei, Jeong, Lak Shin, Chu, Yiwei, Qi, Hui, Yang, Meng, Hoffman, Robert M., Dong, Ziming, Jia, Lijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496198/ https://www.ncbi.nlm.nih.gov/pubmed/25797246 |
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