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Cytoplasmic accumulation of NCoR in malignant melanoma: consequences of altered gene repression and prognostic significance

Invasive malignant melanoma (MM) is an aggressive tumor with no curative therapy available in advanced stages. Nuclear corepressor (NCoR) is an essential regulator of gene transcription, and its function has been found deregulated in different types of cancer. In colorectal cancer cells, loss of nuc...

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Detalles Bibliográficos
Autores principales: Gallardo, Fernando, Padrón, Andreina, Garcia-Carbonell, Ricard, Rius, Cristina, González-Perez, Abel, Arumí-Uria, Montserrat, Iglesias, Mar, Nonell, Lara, Bellosillo, Beatriz, Segura, Sonia, Pujol, Ramon Maria, Lopez-Bigas, Nuria, Bertran, Joan, Bigas, Anna, Espinosa, Lluís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496217/
https://www.ncbi.nlm.nih.gov/pubmed/25823659