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TRAIL-R2 promotes skeletal metastasis in a breast cancer xenograft mouse model
Despite improvements in detection, surgical approaches and systemic therapies, breast cancer remains typically incurable once distant metastases occur. High expression of TRAIL-R2 was found to be associated with poor prognostic parameters in breast cancer patients, suggesting an oncogenic function o...
Autores principales: | Fritsche, Hendrik, Heilmann, Thorsten, Tower, Robert J., Hauser, Charlotte, von Au, Anja, El-Sheikh, Doaa, Campbell, Graeme M., Alp, Göhkan, Schewe, Denis, Hübner, Sebastian, Tiwari, Sanjay, Kownatzki, Daniel, Boretius, Susann, Adam, Dieter, Jonat, Walter, Becker, Thomas, Glüer, Claus C., Zöller, Margot, Kalthoff, Holger, Schem, Christian, Trauzold, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496234/ https://www.ncbi.nlm.nih.gov/pubmed/25909161 |
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