Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver

Activation of the PI3K and Yes-associated protein (Yap) signaling pathways has been independently reported in human hepatocellular carcinoma (HCC). However, the oncogenic interactions between these two cascades in hepatocarcinogenesis remain undetermined. To assess the consequences of the crosstalk...

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Detalles Bibliográficos
Autores principales: Li, Xiaolei, Tao, Junyan, Cigliano, Antonio, Sini, Marcella, Calderaro, Julien, Azoulay, Daniel, Wang, Chunmei, Liu, Yan, Jiang, Lijie, Evert, Katja, Demartis, Maria I., Ribback, Silvia, Utpatel, Kirsten, Dombrowski, Frank, Evert, Matthias, Calvisi, Diego F., Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496343/
https://www.ncbi.nlm.nih.gov/pubmed/25826091

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