HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity

HIPK2, a cell fate decision kinase inactivated in several human cancers, is thought to exert its oncosuppressing activity through its p53-dependent and -independent apoptotic function. However, a HIPK2 role in cell proliferation has also been described. In particular, HIPK2 is required to complete c...

Descripción completa

Detalles Bibliográficos
Autores principales: Valente, Davide, Bossi, Gianluca, Moncada, Alice, Tornincasa, Mara, Indelicato, Stefania, Piscuoglio, Salvatore, Karamitopoulou, Eva Diamantis, Bartolazzi, Armando, Pierantoni, Giovanna Maria, Fusco, Alfredo, Soddu, Silvia, Rinaldo, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496358/
https://www.ncbi.nlm.nih.gov/pubmed/25868975

Ejemplares similares

Ejemplares similares