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Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models
To assess the therapeutic outcome of selective block of VEGFR1, we have evaluated the activity of a new specific antagonist of VEGFR1, named iVR1 (inhibitor of VEGFR1), in syngenic and xenograft colorectal cancer models, in an artificial model of metastatization, and in laser-induced choroid neovasc...
Autores principales: | Cicatiello, Valeria, Apicella, Ivana, Tudisco, Laura, Tarallo, Valeria, Formisano, Luigi, Sandomenico, Annamaria, Kim, Younghee, Bastos-Carvalho, Ana, Orlandi, Augusto, Ambati, Jayakrishna, Ruvo, Menotti, Bianco, Roberto, De Falco, Sandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496375/ https://www.ncbi.nlm.nih.gov/pubmed/25868854 |
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