Forced expression of fibroblast growth factor 21 reverses the sustained impairment of liver regeneration in hPPARα(PAC) mice due to dysregulated bile acid synthesis

Peroxisome proliferator activated receptor α (PPARα) stimulates hepatocellular proliferation is species-specific. Activation of mouse, but not human, PPARα induces hepatocellular proliferation, hepatomegaly, and liver cancer. Here we tested the hypothesis that human and mouse PPARα affects liver reg...

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Detalles Bibliográficos
Autores principales: Liu, Hui-Xin, Hu, Ying, French, Samuel W., Gonzalez, Frank J., Wan, Yu-Jui Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Pathology: Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496390/
https://www.ncbi.nlm.nih.gov/pubmed/25991671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496390/
https://www.ncbi.nlm.nih.gov/pubmed/25991671

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