Asymmetric Lipid Membranes: Towards More Realistic Model Systems

Despite the ubiquity of transbilayer asymmetry in natural cell membranes, the vast majority of existing research has utilized chemically well-defined symmetric liposomes, where the inner and outer bilayer leaflets have the same composition. Here, we review various aspects of asymmetry in nature and...

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Detalles Bibliográficos
Autores principales: Marquardt, Drew, Geier, Barbara, Pabst, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496639/
https://www.ncbi.nlm.nih.gov/pubmed/25955841
http://dx.doi.org/10.3390/membranes5020180
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author Marquardt, Drew
Geier, Barbara
Pabst, Georg
author_facet Marquardt, Drew
Geier, Barbara
Pabst, Georg
author_sort Marquardt, Drew
collection PubMed
description Despite the ubiquity of transbilayer asymmetry in natural cell membranes, the vast majority of existing research has utilized chemically well-defined symmetric liposomes, where the inner and outer bilayer leaflets have the same composition. Here, we review various aspects of asymmetry in nature and in model systems in anticipation for the next phase of model membrane studies.
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spelling pubmed-44966392015-07-10 Asymmetric Lipid Membranes: Towards More Realistic Model Systems Marquardt, Drew Geier, Barbara Pabst, Georg Membranes (Basel) Review Despite the ubiquity of transbilayer asymmetry in natural cell membranes, the vast majority of existing research has utilized chemically well-defined symmetric liposomes, where the inner and outer bilayer leaflets have the same composition. Here, we review various aspects of asymmetry in nature and in model systems in anticipation for the next phase of model membrane studies. MDPI 2015-05-06 /pmc/articles/PMC4496639/ /pubmed/25955841 http://dx.doi.org/10.3390/membranes5020180 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Marquardt, Drew
Geier, Barbara
Pabst, Georg
Asymmetric Lipid Membranes: Towards More Realistic Model Systems
title Asymmetric Lipid Membranes: Towards More Realistic Model Systems
title_full Asymmetric Lipid Membranes: Towards More Realistic Model Systems
title_fullStr Asymmetric Lipid Membranes: Towards More Realistic Model Systems
title_full_unstemmed Asymmetric Lipid Membranes: Towards More Realistic Model Systems
title_short Asymmetric Lipid Membranes: Towards More Realistic Model Systems
title_sort asymmetric lipid membranes: towards more realistic model systems
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496639/
https://www.ncbi.nlm.nih.gov/pubmed/25955841
http://dx.doi.org/10.3390/membranes5020180
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