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Large-scale Direct Targeting for Drug Repositioning and Discovery
A system-level identification of drug-target direct interactions is vital to drug repositioning and discovery. However, the biological means on a large scale remains challenging and expensive even nowadays. The available computational models mainly focus on predicting indirect interactions or direct...
Autores principales: | Zheng, Chunli, Guo, Zihu, Huang, Chao, Wu, Ziyin, Li, Yan, Chen, Xuetong, Fu, Yingxue, Ru, Jinlong, Ali Shar, Piar, Wang, Yuan, Wang, Yonghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496667/ https://www.ncbi.nlm.nih.gov/pubmed/26155766 http://dx.doi.org/10.1038/srep11970 |
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