Cargando…
Posttranslational Modifications and Clearing of α-Synuclein Aggregates in Yeast
The budding yeast Saccharomyces cerevisiae represents an established model system to study the molecular mechanisms associated to neurodegenerative disorders. A key-feature of Parkinson’s disease is the formation of Lewy bodies, which are cytoplasmic protein inclusions. Misfolded α-synuclein is one...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496687/ https://www.ncbi.nlm.nih.gov/pubmed/25915624 http://dx.doi.org/10.3390/biom5020617 |