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Posttranslational Modifications and Clearing of α-Synuclein Aggregates in Yeast

The budding yeast Saccharomyces cerevisiae represents an established model system to study the molecular mechanisms associated to neurodegenerative disorders. A key-feature of Parkinson’s disease is the formation of Lewy bodies, which are cytoplasmic protein inclusions. Misfolded α-synuclein is one...

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Detalles Bibliográficos
Autores principales:	Popova, Blagovesta, Kleinknecht, Alexandra, Braus, Gerhard H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496687/ https://www.ncbi.nlm.nih.gov/pubmed/25915624 http://dx.doi.org/10.3390/biom5020617

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