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Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae)
Plants of the Lauraceae family are widely used in traditional medicine and are sources of various classes of secondary metabolites. Two genera of this family, Beilschmiedia and Endiandra, have been the subject of numerous investigations over the past decades because of their application in tradition...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496702/ https://www.ncbi.nlm.nih.gov/pubmed/26117852 http://dx.doi.org/10.3390/biom5020910 |
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author | Ndjakou Lenta, Bruno Chouna, Jean Rodolphe Nkeng-Efouet, Pepin Alango Sewald, Norbert |
author_facet | Ndjakou Lenta, Bruno Chouna, Jean Rodolphe Nkeng-Efouet, Pepin Alango Sewald, Norbert |
author_sort | Ndjakou Lenta, Bruno |
collection | PubMed |
description | Plants of the Lauraceae family are widely used in traditional medicine and are sources of various classes of secondary metabolites. Two genera of this family, Beilschmiedia and Endiandra, have been the subject of numerous investigations over the past decades because of their application in traditional medicine. They are the only source of bioactive endiandric acid derivatives. Noteworthy is that their biosynthesis contains two consecutive non-enzymatic electrocyclic reactions. Several interesting biological activities for this specific class of secondary metabolites and other constituents of the two genera have been reported, including antimicrobial, enzymes inhibitory and cytotoxic properties. This review compiles information on the structures of the compounds described between January 1960 and March 2015, their biological activities and information on endiandric acid biosynthesis, with 104 references being cited. |
format | Online Article Text |
id | pubmed-4496702 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-44967022015-07-10 Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae) Ndjakou Lenta, Bruno Chouna, Jean Rodolphe Nkeng-Efouet, Pepin Alango Sewald, Norbert Biomolecules Review Plants of the Lauraceae family are widely used in traditional medicine and are sources of various classes of secondary metabolites. Two genera of this family, Beilschmiedia and Endiandra, have been the subject of numerous investigations over the past decades because of their application in traditional medicine. They are the only source of bioactive endiandric acid derivatives. Noteworthy is that their biosynthesis contains two consecutive non-enzymatic electrocyclic reactions. Several interesting biological activities for this specific class of secondary metabolites and other constituents of the two genera have been reported, including antimicrobial, enzymes inhibitory and cytotoxic properties. This review compiles information on the structures of the compounds described between January 1960 and March 2015, their biological activities and information on endiandric acid biosynthesis, with 104 references being cited. MDPI 2015-05-14 /pmc/articles/PMC4496702/ /pubmed/26117852 http://dx.doi.org/10.3390/biom5020910 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Ndjakou Lenta, Bruno Chouna, Jean Rodolphe Nkeng-Efouet, Pepin Alango Sewald, Norbert Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae) |
title | Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae) |
title_full | Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae) |
title_fullStr | Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae) |
title_full_unstemmed | Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae) |
title_short | Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae) |
title_sort | endiandric acid derivatives and other constituents of plants from the genera beilschmiedia and endiandra (lauraceae) |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496702/ https://www.ncbi.nlm.nih.gov/pubmed/26117852 http://dx.doi.org/10.3390/biom5020910 |
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