A Perspective on the Enhancer Dependent Bacterial RNA Polymerase

Here we review recent findings and offer a perspective on how the major variant RNA polymerase of bacteria, which contains the sigma54 factor, functions for regulated gene expression. We consider what gaps exist in our understanding of its genetic, biochemical and biophysical functioning and how the...

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Detalles Bibliográficos
Autores principales: Zhang, Nan, Buck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496707/
https://www.ncbi.nlm.nih.gov/pubmed/26010401
http://dx.doi.org/10.3390/biom5021012
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author Zhang, Nan
Buck, Martin
author_facet Zhang, Nan
Buck, Martin
author_sort Zhang, Nan
collection PubMed
description Here we review recent findings and offer a perspective on how the major variant RNA polymerase of bacteria, which contains the sigma54 factor, functions for regulated gene expression. We consider what gaps exist in our understanding of its genetic, biochemical and biophysical functioning and how they might be addressed.
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spelling pubmed-44967072015-07-10 A Perspective on the Enhancer Dependent Bacterial RNA Polymerase Zhang, Nan Buck, Martin Biomolecules Review Here we review recent findings and offer a perspective on how the major variant RNA polymerase of bacteria, which contains the sigma54 factor, functions for regulated gene expression. We consider what gaps exist in our understanding of its genetic, biochemical and biophysical functioning and how they might be addressed. MDPI 2015-05-21 /pmc/articles/PMC4496707/ /pubmed/26010401 http://dx.doi.org/10.3390/biom5021012 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Nan
Buck, Martin
A Perspective on the Enhancer Dependent Bacterial RNA Polymerase
title A Perspective on the Enhancer Dependent Bacterial RNA Polymerase
title_full A Perspective on the Enhancer Dependent Bacterial RNA Polymerase
title_fullStr A Perspective on the Enhancer Dependent Bacterial RNA Polymerase
title_full_unstemmed A Perspective on the Enhancer Dependent Bacterial RNA Polymerase
title_short A Perspective on the Enhancer Dependent Bacterial RNA Polymerase
title_sort perspective on the enhancer dependent bacterial rna polymerase
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496707/
https://www.ncbi.nlm.nih.gov/pubmed/26010401
http://dx.doi.org/10.3390/biom5021012
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