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Regulation of Transcription Elongation and Termination
This article will review our current understanding of transcription elongation and termination in E. coli. We discuss why transcription elongation complexes pause at certain template sites and how auxiliary host and phage transcription factors affect elongation and termination. The connection betwee...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496710/ https://www.ncbi.nlm.nih.gov/pubmed/26035374 http://dx.doi.org/10.3390/biom5021063 |
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author | Washburn, Robert S. Gottesman, Max E. |
author_facet | Washburn, Robert S. Gottesman, Max E. |
author_sort | Washburn, Robert S. |
collection | PubMed |
description | This article will review our current understanding of transcription elongation and termination in E. coli. We discuss why transcription elongation complexes pause at certain template sites and how auxiliary host and phage transcription factors affect elongation and termination. The connection between translation and transcription elongation is described. Finally we present an overview indicating where progress has been made and where it has not. |
format | Online Article Text |
id | pubmed-4496710 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-44967102015-07-10 Regulation of Transcription Elongation and Termination Washburn, Robert S. Gottesman, Max E. Biomolecules Review This article will review our current understanding of transcription elongation and termination in E. coli. We discuss why transcription elongation complexes pause at certain template sites and how auxiliary host and phage transcription factors affect elongation and termination. The connection between translation and transcription elongation is described. Finally we present an overview indicating where progress has been made and where it has not. MDPI 2015-05-29 /pmc/articles/PMC4496710/ /pubmed/26035374 http://dx.doi.org/10.3390/biom5021063 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Washburn, Robert S. Gottesman, Max E. Regulation of Transcription Elongation and Termination |
title | Regulation of Transcription Elongation and Termination |
title_full | Regulation of Transcription Elongation and Termination |
title_fullStr | Regulation of Transcription Elongation and Termination |
title_full_unstemmed | Regulation of Transcription Elongation and Termination |
title_short | Regulation of Transcription Elongation and Termination |
title_sort | regulation of transcription elongation and termination |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496710/ https://www.ncbi.nlm.nih.gov/pubmed/26035374 http://dx.doi.org/10.3390/biom5021063 |
work_keys_str_mv | AT washburnroberts regulationoftranscriptionelongationandtermination AT gottesmanmaxe regulationoftranscriptionelongationandtermination |