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Interaction between Neuromelanin and Alpha-Synuclein in Parkinson’s Disease

Parkinson’s disease (PD) is a very common neurodegenerative disorder characterized by the accumulation of α-synuclein (α-syn) into Lewy body (LB) inclusions and the loss of neuronmelanin (NM) containing dopamine (DA) neurons in the substantia nigra (SN). Pathological α-syn and NM are two prominent h...

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Detalles Bibliográficos
Autores principales: Xu, Shengli, Chan, Piu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496713/
https://www.ncbi.nlm.nih.gov/pubmed/26057626
http://dx.doi.org/10.3390/biom5021122