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Efficient introgression of allelic variants by embryo-mediated editing of the bovine genome
The recent development of designer nucleases allows for the efficient and precise introduction of genetic change into livestock genomes. Most studies so far have focused on the introduction of random mutations in cultured cells and the use of nuclear transfer to generate animals with edited genotype...
Autores principales: | Wei, Jingwei, Wagner, Stefan, Lu, Dan, Maclean, Paul, Carlson, Daniel F., Fahrenkrug, Scott C., Laible, Götz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496724/ https://www.ncbi.nlm.nih.gov/pubmed/26156133 http://dx.doi.org/10.1038/srep11735 |
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