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Efficient introgression of allelic variants by embryo-mediated editing of the bovine genome

The recent development of designer nucleases allows for the efficient and precise introduction of genetic change into livestock genomes. Most studies so far have focused on the introduction of random mutations in cultured cells and the use of nuclear transfer to generate animals with edited genotype...

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Detalles Bibliográficos
Autores principales: Wei, Jingwei, Wagner, Stefan, Lu, Dan, Maclean, Paul, Carlson, Daniel F., Fahrenkrug, Scott C., Laible, Götz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496724/
https://www.ncbi.nlm.nih.gov/pubmed/26156133
http://dx.doi.org/10.1038/srep11735

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