Evaluation of BLAST-based edge-weighting metrics used for homology inference with the Markov Clustering algorithm

BACKGROUND: Clustering protein sequences according to inferred homology is a fundamental step in the analysis of many large data sets. Since the publication of the Markov Clustering (MCL) algorithm in 2002, it has been the centerpiece of several popular applications. Each of these approaches generat...

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Detalles Bibliográficos
Autores principales: Gibbons, Theodore R., Mount, Stephen M., Cooper, Endymion D., Delwiche, Charles F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496851/
https://www.ncbi.nlm.nih.gov/pubmed/26160651
http://dx.doi.org/10.1186/s12859-015-0625-x

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