Focal segmental glomerulosclerosis: molecular genetics and targeted therapies

Recent advances show that human focal segmental glomerulosclerosis (FSGS) is a primary podocytopathy caused by podocyte-specific gene mutations including NPHS1, NPHS2, WT-1, LAMB2, CD2AP, TRPC6, ACTN4 and INF2. This review focuses on genes discovered in the investigation of complex FSGS pathomechani...

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Detalles Bibliográficos
Autores principales: Chen, Ying Maggie, Liapis, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496884/
https://www.ncbi.nlm.nih.gov/pubmed/26156092
http://dx.doi.org/10.1186/s12882-015-0090-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496884/
https://www.ncbi.nlm.nih.gov/pubmed/26156092
http://dx.doi.org/10.1186/s12882-015-0090-9

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