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Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum

BACKGROUND: The aim of this study was to develop site-specific antibodies as a tool to capture Plasmodium falciparum-dihydrofolate reductase (Pf-DHFR) from blood samples from P. falciparum infected individuals in order to detect, in a sandwich ELISA, structural alterations due to point mutations in...

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Detalles Bibliográficos
Autores principales:	Alifrangis, Michael, Christensen, Inge T, Jørgensen, Flemming S, Rønn, Anita M, Weng, Jimmy E, Chen, Ming, Bygbjerg, Ib C, Sirawaraporn, Worachart, Palarasah, Yaseelan, Koch, Claus
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449723/ https://www.ncbi.nlm.nih.gov/pubmed/15193156 http://dx.doi.org/10.1186/1475-2875-3-16

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