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Fast Proton Exchange in Histidine: Measurement of Rate Constants through Indirect Detection by NMR Spectroscopy

Owing to its imidazole side chain, histidine participates in various processes such as enzyme catalysis, pH regulation, metal binding, and phosphorylation. The determination of exchange rates of labile protons for such a system is important for understanding its functions. However, these rates are t...

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Detalles Bibliográficos
Autores principales: Sehgal, Akansha Ashvani, Duma, Luminita, Bodenhausen, Geoffrey, Pelupessy, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497323/
https://www.ncbi.nlm.nih.gov/pubmed/24719307
http://dx.doi.org/10.1002/chem.201304992

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