Structural Effects in Lithiocuprate Chemistry: The Elucidation of Reactive Pentametallic Complexes

TMPLi (TMP=2,2,6,6-tetramethylpiperidide) reacts with Cu(I) salts in the presence of Et(2)O to give the dimers [{(TMP)(2)Cu(X)Li(2)(OEt(2))}(2)] (X=CN, halide). In contrast, the use of DMPLi (DMP=cis-2,6-dimethylpiperidide) gives an unprecedented structural motif; [{(DMP)(2)CuLi(OEt(2))}(2)LiX] (X=h...

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Autores principales: Harford, Philip J, Peel, Andrew J, Taylor, Joseph P, Komagawa, Shinsuke, Raithby, Paul R, Robinson, Thomas P, Uchiyama, Masanobu, Wheatley, Andrew E H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497349/
https://www.ncbi.nlm.nih.gov/pubmed/24550148
http://dx.doi.org/10.1002/chem.201304824
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author Harford, Philip J
Peel, Andrew J
Taylor, Joseph P
Komagawa, Shinsuke
Raithby, Paul R
Robinson, Thomas P
Uchiyama, Masanobu
Wheatley, Andrew E H
author_facet Harford, Philip J
Peel, Andrew J
Taylor, Joseph P
Komagawa, Shinsuke
Raithby, Paul R
Robinson, Thomas P
Uchiyama, Masanobu
Wheatley, Andrew E H
author_sort Harford, Philip J
collection PubMed
description TMPLi (TMP=2,2,6,6-tetramethylpiperidide) reacts with Cu(I) salts in the presence of Et(2)O to give the dimers [{(TMP)(2)Cu(X)Li(2)(OEt(2))}(2)] (X=CN, halide). In contrast, the use of DMPLi (DMP=cis-2,6-dimethylpiperidide) gives an unprecedented structural motif; [{(DMP)(2)CuLi(OEt(2))}(2)LiX] (X=halide). This formulation suggests a hitherto unexplored route to the in situ formation of Gilman-type bases that are of proven reactivity in directed ortho cupration.
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spelling pubmed-44973492015-07-10 Structural Effects in Lithiocuprate Chemistry: The Elucidation of Reactive Pentametallic Complexes Harford, Philip J Peel, Andrew J Taylor, Joseph P Komagawa, Shinsuke Raithby, Paul R Robinson, Thomas P Uchiyama, Masanobu Wheatley, Andrew E H Chemistry Communications TMPLi (TMP=2,2,6,6-tetramethylpiperidide) reacts with Cu(I) salts in the presence of Et(2)O to give the dimers [{(TMP)(2)Cu(X)Li(2)(OEt(2))}(2)] (X=CN, halide). In contrast, the use of DMPLi (DMP=cis-2,6-dimethylpiperidide) gives an unprecedented structural motif; [{(DMP)(2)CuLi(OEt(2))}(2)LiX] (X=halide). This formulation suggests a hitherto unexplored route to the in situ formation of Gilman-type bases that are of proven reactivity in directed ortho cupration. WILEY-VCH Verlag 2014-04-01 2014-02-19 /pmc/articles/PMC4497349/ /pubmed/24550148 http://dx.doi.org/10.1002/chem.201304824 Text en © 2014 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. http://creativecommons.org/licenses/by/3.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Harford, Philip J
Peel, Andrew J
Taylor, Joseph P
Komagawa, Shinsuke
Raithby, Paul R
Robinson, Thomas P
Uchiyama, Masanobu
Wheatley, Andrew E H
Structural Effects in Lithiocuprate Chemistry: The Elucidation of Reactive Pentametallic Complexes
title Structural Effects in Lithiocuprate Chemistry: The Elucidation of Reactive Pentametallic Complexes
title_full Structural Effects in Lithiocuprate Chemistry: The Elucidation of Reactive Pentametallic Complexes
title_fullStr Structural Effects in Lithiocuprate Chemistry: The Elucidation of Reactive Pentametallic Complexes
title_full_unstemmed Structural Effects in Lithiocuprate Chemistry: The Elucidation of Reactive Pentametallic Complexes
title_short Structural Effects in Lithiocuprate Chemistry: The Elucidation of Reactive Pentametallic Complexes
title_sort structural effects in lithiocuprate chemistry: the elucidation of reactive pentametallic complexes
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497349/
https://www.ncbi.nlm.nih.gov/pubmed/24550148
http://dx.doi.org/10.1002/chem.201304824
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