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Therapeutic manipulation of angiogenesis with miR-27b

BACKGROUND: Multiple studies demonstrated pro-angiogenic effects of microRNA (miR)-27b. Its targets include Notch ligand Dll4, Sprouty (Spry)-2, PPARγ and Semaphorin (SEMA) 6A. miR-27 effects in the heart are context-dependent: although it is necessary for ventricular maturation, targeted overexpres...

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Detalles Bibliográficos
Autores principales:	Veliceasa, Dorina, Biyashev, Dauren, Qin, Gangjian, Misener, Sol, Mackie, Alexander Roy, Kishore, Raj, Volpert, Olga V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497374/ https://www.ncbi.nlm.nih.gov/pubmed/26161255 http://dx.doi.org/10.1186/s13221-015-0031-1

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