The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines**

Allylrhodium species generated from potassium allyltrifluoroborates can undergo isomerization by 1,4-rhodium(I) migration to give more complex isomers, which then react with cyclic imines to provide products with up to three new stereochemical elements. High enantioselectivities are obtained using c...

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Detalles Bibliográficos
Autores principales: Hepburn, Hamish B, Lam, Hon Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497600/
https://www.ncbi.nlm.nih.gov/pubmed/25205604
http://dx.doi.org/10.1002/anie.201407233
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author Hepburn, Hamish B
Lam, Hon Wai
author_facet Hepburn, Hamish B
Lam, Hon Wai
author_sort Hepburn, Hamish B
collection PubMed
description Allylrhodium species generated from potassium allyltrifluoroborates can undergo isomerization by 1,4-rhodium(I) migration to give more complex isomers, which then react with cyclic imines to provide products with up to three new stereochemical elements. High enantioselectivities are obtained using chiral diene–rhodium complexes.
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spelling pubmed-44976002015-07-10 The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines** Hepburn, Hamish B Lam, Hon Wai Angew Chem Int Ed Engl Communications Allylrhodium species generated from potassium allyltrifluoroborates can undergo isomerization by 1,4-rhodium(I) migration to give more complex isomers, which then react with cyclic imines to provide products with up to three new stereochemical elements. High enantioselectivities are obtained using chiral diene–rhodium complexes. WILEY-VCH Verlag 2014-10-20 2014-09-09 /pmc/articles/PMC4497600/ /pubmed/25205604 http://dx.doi.org/10.1002/anie.201407233 Text en © 2014 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.
spellingShingle Communications
Hepburn, Hamish B
Lam, Hon Wai
The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines**
title The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines**
title_full The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines**
title_fullStr The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines**
title_full_unstemmed The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines**
title_short The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines**
title_sort isomerization of allylrhodium intermediates in the rhodium-catalyzed nucleophilic allylation of cyclic imines**
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497600/
https://www.ncbi.nlm.nih.gov/pubmed/25205604
http://dx.doi.org/10.1002/anie.201407233
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