TORC1 Inhibition by Rapamycin Promotes Antioxidant Defences in a Drosophila Model of Friedreich’s Ataxia

Friedreich’s ataxia (FRDA), the most common inherited ataxia in the Caucasian population, is a multisystemic disease caused by a significant decrease in the frataxin level. To identify genes capable of modifying the severity of the symptoms of frataxin depletion, we performed a candidate genetic scr...

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Detalles Bibliográficos
Autores principales: Calap-Quintana, Pablo, Soriano, Sirena, Llorens, José Vicente, Al-Ramahi, Ismael, Botas, Juan, Moltó, María Dolores, Martínez-Sebastián, María José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497667/
https://www.ncbi.nlm.nih.gov/pubmed/26158631
http://dx.doi.org/10.1371/journal.pone.0132376

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