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β1 Integrins Mediate Attachment of Mesenchymal Stem Cells to Cartilage Lesions

Mesenchymal stem cells (MSC) may have great potential for cell-based therapies of osteoarthritis. However, after injection in the joint, only few cells adhere to defective articular cartilage and contribute to cartilage regeneration. Little is known about the molecular mechanisms of MSC attachment t...

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Detalles Bibliográficos
Autores principales: Zwolanek, Daniela, Flicker, Magdalena, Kirstätter, Elisabeth, Zaucke, Frank, van Osch, Gerjo J.V.M., Erben, Reinhold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497673/
https://www.ncbi.nlm.nih.gov/pubmed/26309781
http://dx.doi.org/10.1089/biores.2014.0055