The Broad Neutralizing Antibody Responses after HIV-1 Superinfection Are Not Dominated by Antibodies Directed to Epitopes Common in Single Infection

HIV-1 vaccines designed to date have failed to elicit neutralizing antibodies (Nabs) that are capable of protecting against globally diverse HIV-1 subtypes. One relevant setting to study the development of a strong, cross-reactive Nab response is HIV-1 superinfection (SI), defined as sequential infe...

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Detalles Bibliográficos
Autores principales: Cortez, Valerie, Wang, Bingjie, Dingens, Adam, Chen, Mitchell M., Ronen, Keshet, Georgiev, Ivelin S., McClelland, R. Scott, Overbaugh, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497680/
https://www.ncbi.nlm.nih.gov/pubmed/26158467
http://dx.doi.org/10.1371/journal.ppat.1004973

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