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Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells

Tamoxifen resistance is often observed in the majority of estrogen receptor–positive breast cancers and it remains as a serious clinical problem in breast cancer management. Increased aerobic glycolysis has been proposed as one of the mechanisms for acquired resistance to chemotherapeutic agents in...

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Detalles Bibliográficos
Autores principales:	Woo, Yu Mi, Shin, Yubin, Lee, Eun Ji, Lee, Sunyoung, Jeong, Seung Hun, Kong, Hyun Kyung, Park, Eun Young, Kim, Hyoung Kyu, Han, Jin, Chang, Minsun, Park, Jong-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497721/ https://www.ncbi.nlm.nih.gov/pubmed/26158266 http://dx.doi.org/10.1371/journal.pone.0132285

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