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Abnormal Accumulation of Collagen Type I Due to the Loss of Discoidin Domain Receptor 2 (Ddr2) Promotes Testicular Interstitial Dysfunction
BACKGROUND: Loss of functional allele for discoidin domain receptor 2 (Ddr2) results in impaired Leydig cell response to luteinizing hormone (LH), low testosterone production and arrested spermatogenesis in older male Ddr2(slie/slie) mice. However, the underlying mechanism responsible for this pheno...
Autores principales: | Zhu, Chu-chao, Tang, Bin, Su, Jin, Zhao, Hu, Bu, Xin, Li, Zhen, Zhao, Jie, Gong, Wei-dong, Wu, Zhi-qun, Yao, Li-bo, Li, Wei, Zhang, Yuan-qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497730/ https://www.ncbi.nlm.nih.gov/pubmed/26158267 http://dx.doi.org/10.1371/journal.pone.0131947 |
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