A Chromosomal Memory Triggered by Xist Regulates Histone Methylation in X Inactivation

We have elucidated the kinetics of histone methylation during X inactivation using an inducible Xist expression system in mouse embryonic stem (ES) cells. Previous reports showed that the ability of Xist to trigger silencing is restricted to an early window in ES cell differentiation. Here we show t...

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Detalles Bibliográficos
Autores principales: Kohlmaier, Alexander, Savarese, Fabio, Lachner, Monika, Martens, Joost, Jenuwein, Thomas, Wutz, Anton
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449785/
https://www.ncbi.nlm.nih.gov/pubmed/15252442
http://dx.doi.org/10.1371/journal.pbio.0020171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449785/
https://www.ncbi.nlm.nih.gov/pubmed/15252442
http://dx.doi.org/10.1371/journal.pbio.0020171

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