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A Chromosomal Memory Triggered by Xist Regulates Histone Methylation in X Inactivation
We have elucidated the kinetics of histone methylation during X inactivation using an inducible Xist expression system in mouse embryonic stem (ES) cells. Previous reports showed that the ability of Xist to trigger silencing is restricted to an early window in ES cell differentiation. Here we show t...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC449785/ https://www.ncbi.nlm.nih.gov/pubmed/15252442 http://dx.doi.org/10.1371/journal.pbio.0020171 |