The diagnosis of left ventricular assist device thrombosis

The clinical course of a patient with a left ventricular assist device is described. A total of 6 weeks after device insertion, the lactate dehydrogenase (LDH) level increased to 2801 U/l despite adding low-molecular-weight heparin to acenocoumarol and aspirin. Pump thrombosis was suspected but unco...

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Detalles Bibliográficos
Autores principales: Gerds, H.Z.R., Brügemann, J., Rienstra, M., Erasmus, M.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bohn Stafleu van Loghum 2015
Materias:
Heart Beat
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497989/
https://www.ncbi.nlm.nih.gov/pubmed/26041406
http://dx.doi.org/10.1007/s12471-015-0705-6
Descripción
Sumario:The clinical course of a patient with a left ventricular assist device is described. A total of 6 weeks after device insertion, the lactate dehydrogenase (LDH) level increased to 2801 U/l despite adding low-molecular-weight heparin to acenocoumarol and aspirin. Pump thrombosis was suspected but unconfirmed by computed tomography. Increased pump power requirement did not occur. Instituting unfractionated heparin caused a drop in the LDH level. After discontinuing heparin, the LDH levels rose to 5529 U/l whereupon pump replacement was performed. LDH levels, combined with clinical deterioration and right heart catheterisation, led to the diagnosis of pump thrombosis.

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