The diagnosis of left ventricular assist device thrombosis

The clinical course of a patient with a left ventricular assist device is described. A total of 6 weeks after device insertion, the lactate dehydrogenase (LDH) level increased to 2801 U/l despite adding low-molecular-weight heparin to acenocoumarol and aspirin. Pump thrombosis was suspected but unco...

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Autores principales: Gerds, H.Z.R., Brügemann, J., Rienstra, M., Erasmus, M.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bohn Stafleu van Loghum 2015
Materias:
Heart Beat
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497989/
https://www.ncbi.nlm.nih.gov/pubmed/26041406
http://dx.doi.org/10.1007/s12471-015-0705-6
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author Gerds, H.Z.R.
Brügemann, J.
Rienstra, M.
Erasmus, M.E.
author_facet Gerds, H.Z.R.
Brügemann, J.
Rienstra, M.
Erasmus, M.E.
author_sort Gerds, H.Z.R.
collection PubMed
description The clinical course of a patient with a left ventricular assist device is described. A total of 6 weeks after device insertion, the lactate dehydrogenase (LDH) level increased to 2801 U/l despite adding low-molecular-weight heparin to acenocoumarol and aspirin. Pump thrombosis was suspected but unconfirmed by computed tomography. Increased pump power requirement did not occur. Instituting unfractionated heparin caused a drop in the LDH level. After discontinuing heparin, the LDH levels rose to 5529 U/l whereupon pump replacement was performed. LDH levels, combined with clinical deterioration and right heart catheterisation, led to the diagnosis of pump thrombosis.
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spelling pubmed-44979892015-07-15 The diagnosis of left ventricular assist device thrombosis Gerds, H.Z.R. Brügemann, J. Rienstra, M. Erasmus, M.E. Neth Heart J Heart Beat The clinical course of a patient with a left ventricular assist device is described. A total of 6 weeks after device insertion, the lactate dehydrogenase (LDH) level increased to 2801 U/l despite adding low-molecular-weight heparin to acenocoumarol and aspirin. Pump thrombosis was suspected but unconfirmed by computed tomography. Increased pump power requirement did not occur. Instituting unfractionated heparin caused a drop in the LDH level. After discontinuing heparin, the LDH levels rose to 5529 U/l whereupon pump replacement was performed. LDH levels, combined with clinical deterioration and right heart catheterisation, led to the diagnosis of pump thrombosis. Bohn Stafleu van Loghum 2015-06-04 2015-07 /pmc/articles/PMC4497989/ /pubmed/26041406 http://dx.doi.org/10.1007/s12471-015-0705-6 Text en © The Author(s) 2015 https://creativecommons.org/licenses/by/4.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Heart Beat
Gerds, H.Z.R.
Brügemann, J.
Rienstra, M.
Erasmus, M.E.
The diagnosis of left ventricular assist device thrombosis
title The diagnosis of left ventricular assist device thrombosis
title_full The diagnosis of left ventricular assist device thrombosis
title_fullStr The diagnosis of left ventricular assist device thrombosis
title_full_unstemmed The diagnosis of left ventricular assist device thrombosis
title_short The diagnosis of left ventricular assist device thrombosis
title_sort diagnosis of left ventricular assist device thrombosis
topic Heart Beat
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497989/
https://www.ncbi.nlm.nih.gov/pubmed/26041406
http://dx.doi.org/10.1007/s12471-015-0705-6
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