Imaging of reactive oxygen species using [(3)H]hydromethidine in mice with cisplatin-induced nephrotoxicity

BACKGROUND: Reactive oxygen species (ROS) have been implicated in cisplatin-induced nephrotoxicity. The aim of this study was to investigate the potential of using [(3)H]-labeled N-methyl-2,3-diamino-6-phenyl-dihydrophenanthridine ([(3)H]hydromethidine) for ex vivo imaging of regional ROS overproduc...

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Detalles Bibliográficos
Autores principales: Takai, Nozomi, Abe, Kohji, Tonomura, Misato, Imamoto, Natsumi, Fukumoto, Kazumi, Ito, Miwa, Momosaki, Sotaro, Fujisawa, Kae, Morimoto, Kenji, Takasu, Nobuo, Inoue, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497996/
https://www.ncbi.nlm.nih.gov/pubmed/26160497
http://dx.doi.org/10.1186/s13550-015-0116-0

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