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Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice
Nuclear RNA export factors (NXF) are conserved in all metazoans and are deemed essential for shuttling RNA across the nuclear envelope and other post-transcriptional processes (such as mRNA metabolism, storage and stability). Disruption of human NXF5 has been implicated in intellectual and psychosoc...
Autores principales: | Callaerts-Vegh, Zsuzsanna, Ahmed, Tariq, Vermaercke, Ben, Marynen, Peter, Balschun, Detlef, Froyen, Guy, D’Hooge, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498129/ https://www.ncbi.nlm.nih.gov/pubmed/26217206 http://dx.doi.org/10.3389/fnbeh.2015.00179 |
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