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Oxytocin evokes a pulsatile PGE2 release from ileum mucosa and is required for repair of intestinal epithelium after injury

We measured the short-circuit current (I(sc)) in rat ileum mucosa to identify the effect of oxytocin (OT) on mucosal secretion in small intestine. We identified a COX-2-derived pulsatile PGE2 release triggered by OT in rat ileum mucosa. OT receptors (OTR) are expressed in intestine crypt epithelial...

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Detalles Bibliográficos
Autores principales: Chen, Dawei, Zhao, Junhan, Wang, Haoyi, An, Ning, Zhou, Yuping, Fan, Jiahui, Luo, Junwen, Su, Wenlong, Liu, Chuanyong, Li, Jingxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498177/
https://www.ncbi.nlm.nih.gov/pubmed/26159321
http://dx.doi.org/10.1038/srep11731