Cargando…
A Nanotechnology-Based Platform for Extending the Pharmacokinetic and Binding Properties of Anti-methamphetamine Antibody Fragments
To address the need for effective medications to aid in the treatment of methamphetamine (METH) abuse, we used a nanotechnology approach to customize the in vivo behavior of an anti-METH single chain antibody (scFv7F9Cys). Anti-METH scFv7F9Cys was conjugated to dendrimer nanoparticles via a polyethy...
Autores principales: | Nanaware-Kharade, Nisha, Thakkar, Shraddha, Gonzalez III, Guillermo A., Peterson, Eric C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498229/ https://www.ncbi.nlm.nih.gov/pubmed/26159352 http://dx.doi.org/10.1038/srep12060 |
Ejemplares similares
-
Affinity improvement of a therapeutic antibody to methamphetamine and
amphetamine through structure-based antibody engineering
por: Thakkar, Shraddha, et al.
Publicado: (2014) -
Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse
por: Hay, Charles E., et al.
Publicado: (2018) -
Structural Characterization of a Therapeutic Anti-Methamphetamine Antibody Fragment: Oligomerization and Binding of Active Metabolites
por: Peterson, Eric C., et al.
Publicado: (2013) -
Correction: Structural Characterization of a Therapeutic Anti-Methamphetamine Antibody Fragment: Oligomerization and Binding of Active Metabolites
por: Peterson, Eric C., et al.
Publicado: (2014) -
Nanotechnology in Lung Cancer Therapeutics: A Narrative Review
por: Koutu, Vaibhav, et al.
Publicado: (2023)