Necrotizing Fasciitis in Hematological Patients: Enterobacteriaceae Predominance and Limited Utility of Laboratory Risk Indicator for Necrotizing Fasciitis Score

Immune suppression is a recognized risk factor for necrotizing fasciitis. In patients with hematological malignancies, a profoundly immunocompromised group, the predominant causative organisms are Gram negative. Clinical presentation and outcomes in these patients are similar to the immunocompetent....

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Detalles Bibliográficos
Autores principales: Foo, Rui Min, Tung, Moon Ley, Poon, Li Mei, Chan, Douglas, Smitasin, Nares, Koh, Liang Piu, Chng, Wee Joo, Chai, Louis Yi Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498274/
https://www.ncbi.nlm.nih.gov/pubmed/26180830
http://dx.doi.org/10.1093/ofid/ofv081
Descripción
Sumario:Immune suppression is a recognized risk factor for necrotizing fasciitis. In patients with hematological malignancies, a profoundly immunocompromised group, the predominant causative organisms are Gram negative. Clinical presentation and outcomes in these patients are similar to the immunocompetent. The Laboratory Risk Indicator for Necrotizing Fasciitis score is not reliable for risk stratification of the disease.

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