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Screening for UGT1A1 Genotype in Study A5257 Would Have Markedly Reduced Premature Discontinuation of Atazanavir for Hyperbilirubinemia
Background. Some patients are not prescribed atazanavir because of concern about possible jaundice. Atazanavir-associated hyperbilirubinemia correlates with UGT1A1 rs887829 genotype. We examined bilirubin-related discontinuation of atazanavir in participants from AIDS Clinical Trials Group Study A52...
Autores principales: | Vardhanabhuti, Saran, Ribaudo, Heather J., Landovitz, Raphael J., Ofotokun, Ighovwerha, Lennox, Jeffrey L., Currier, Judith S., Olson, Lana M., Haas, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498287/ https://www.ncbi.nlm.nih.gov/pubmed/26180834 http://dx.doi.org/10.1093/ofid/ofv085 |
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