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Mapping the Hydrogen Bond Networks in the Catalytic Subunit of Protein Kinase A Using H/D Fractionation Factors

[Image: see text] Protein kinase A is a prototypical phosphoryl transferase, sharing its catalytic core (PKA-C) with the entire kinase family. PKA-C substrate recognition, active site organization, and product release depend on the enzyme’s conformational transitions from the open to the closed stat...

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Detalles Bibliográficos
Autores principales:	Li, Geoffrey C., Srivastava, Atul K., Kim, Jonggul, Taylor, Susan S., Veglia, Gianluigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498444/ https://www.ncbi.nlm.nih.gov/pubmed/26030372 http://dx.doi.org/10.1021/acs.biochem.5b00387

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