Cargando…

Iron and hepcidin as risk factors in atherosclerosis: what do the genes say?

BACKGROUND: Previous reports suggested a role for iron and hepcidin in atherosclerosis. Here, we evaluated the causality of these associations from a genetic perspective via (i) a Mendelian randomization (MR) approach, (ii) study of association of atherosclerosis-related single nucleotide polymorphi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Galesloot, Tessel E., Janss, Luc L., Burgess, Stephen, Kiemeney, Lambertus A. L. M., den Heijer, Martin, de Graaf, Jacqueline, Holewijn, Suzanne, Benyamin, Beben, Whitfield, John B., Swinkels, Dorine W., Vermeulen, Sita H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498499/ https://www.ncbi.nlm.nih.gov/pubmed/26159428 http://dx.doi.org/10.1186/s12863-015-0246-4

Ejemplares similares

Cohort Profile: The Nijmegen Biomedical Study (NBS)
por: Galesloot, Tessel E, et al.
Publicado: (2017)

A Comparison of Multivariate Genome-Wide Association Methods
por: Galesloot, Tessel E., et al.
Publicado: (2014)

Meta-GWAS and Meta-Analysis of Exome Array Studies Do Not Reveal Genetic Determinants of Serum Hepcidin
por: Galesloot, Tessel E., et al.
Publicado: (2016)

Known susceptibility SNPs for sporadic prostate cancer show a similar association with “hereditary” prostate cancer
por: Cremers, Ruben G., et al.
Publicado: (2015)

Transferrin Saturation/Hepcidin Ratio Discriminates TMPRSS6-Related Iron Refractory Iron Deficiency Anemia from Patients with Multi-Causal Iron Deficiency Anemia
por: van der Staaij, Hilde, et al.
Publicado: (2022)

Improved Mass Spectrometry Assay For Plasma Hepcidin: Detection and Characterization of a Novel Hepcidin Isoform
por: Laarakkers, Coby M. M., et al.
Publicado: (2013)

Endogenous hepcidin synthesis protects the distal nephron against hemin and hemoglobin mediated necroptosis
por: van Swelm, Rachel P. L., et al.
Publicado: (2018)

Advances in Quantitative Hepcidin Measurements by Time-of-Flight Mass Spectrometry
por: Swinkels, Dorine W., et al.
Publicado: (2008)

Inflammation can increase hepcidin in HFE‐hereditary hemochromatosis
por: Moris, Wenke, et al.
Publicado: (2021)

Iron Status and the Acute Post-Exercise Hepcidin Response in Athletes
por: Peeling, Peter, et al.
Publicado: (2014)

Candidate Gene Sequencing of SLC11A2 and TMPRSS6 in a Family with Severe Anaemia: Common SNPs, Rare Haplotypes, No Causative Mutation
por: Kloss-Brandstätter, Anita, et al.
Publicado: (2012)

Tubular reabsorption and local production of urine hepcidin-25
por: Peters, Hilde PE, et al.
Publicado: (2013)

Urinary Hepcidin Levels in Iron-Deficient and Iron-Supplemented Piglets Correlate with Hepcidin Hepatic mRNA and Serum Levels and with Body Iron Status
por: Staroń, Robert, et al.
Publicado: (2015)

Inflammation-induced hepcidin-25 is associated with the development of anemia in septic patients: an observational study
por: van Eijk, Lucas T, et al.
Publicado: (2011)

A Novel Immunological Assay for Hepcidin Quantification in Human Serum
por: Koliaraki, Vasiliki, et al.
Publicado: (2009)

Hepcidin Status in Cord Blood: Observational Data from a Tertiary Institution in Belgium
por: Ceulemans, Michael, et al.
Publicado: (2023)

A seven day running training period increases basal urinary hepcidin levels as compared to cycling
por: Sim, Marc, et al.
Publicado: (2014)

Unraveling Hepcidin Plasma Protein Binding: Evidence from Peritoneal Equilibration Testing
por: Diepeveen, Laura E., et al.
Publicado: (2019)

Investigating the Molecular Mechanisms of Renal Hepcidin Induction and Protection upon Hemoglobin-Induced Acute Kidney Injury
por: Diepeveen, Laura E., et al.
Publicado: (2022)

An Insight into the Relationships between Hepcidin, Anemia, Infections and Inflammatory Cytokines in Pediatric Refugees: A Cross-Sectional Study
por: Cherian, Sarah, et al.
Publicado: (2008)

Iron Supplementation in Suckling Piglets: How to Correct Iron Deficiency Anemia without Affecting Plasma Hepcidin Levels
por: Starzyński, Rafał R., et al.
Publicado: (2013)

EPO and hepcidin plasma concentrations in blood donors and β‐thalassemia intermedia are not related to commercially tested plasma ERFE concentrations
por: Schotten, Nienke, et al.
Publicado: (2017)

Mass Spectrometry Analysis of Hepcidin Peptides in Experimental Mouse Models
por: Tjalsma, Harold, et al.
Publicado: (2011)

Urinary Bladder Cancer Susceptibility Markers. What Do We Know about Functional Mechanisms?
por: Dudek, Aleksandra M., et al.
Publicado: (2013)

A possible role for hepcidin in the detection of iron deficiency in severely anaemic HIV-infected patients in Malawi
por: Huibers, Minke H. W., et al.
Publicado: (2020)

Menstrual cycle affects iron homeostasis and hepcidin following interval running exercise in endurance-trained women
por: Alfaro-Magallanes, Víctor M., et al.
Publicado: (2022)

Hepcidin response to interval running exercise is not affected by oral contraceptive phase in endurance‐trained women
por: Alfaro‐Magallanes, Víctor M., et al.
Publicado: (2020)

Non-invasive measurements of atherosclerosis in adult cystinosis patients
por: Besouw, Martine T. P., et al.
Publicado: (2011)

Correction to: Menstrual cycle affects iron homeostasis and hepcidin following interval running exercise in endurance-trained women
por: Alfaro-Magallanes, Víctor M., et al.
Publicado: (2022)

Identification of an enhancer region within the TP63/LEPREL1 locus containing genetic variants associated with bladder cancer risk
por: Dudek, Aleksandra M., et al.
Publicado: (2018)

The prognostic value of family history among patients with urinary bladder cancer
por: Egbers, Lieke, et al.
Publicado: (2015)

Smoking intensity and bladder cancer aggressiveness at diagnosis
por: Barbosa, André L. A., et al.
Publicado: (2018)

Intravesical BCG in patients with non-muscle invasive bladder cancer induces trained immunity and decreases respiratory infections
por: van Puffelen, Jelmer H, et al.
Publicado: (2023)

Safety, pharmacokinetics and pharmacodynamics of the anti‐hepcidin Spiegelmer lexaptepid pegol in healthy subjects
por: Boyce, M, et al.
Publicado: (2016)

Low Hepcidin Levels in Severely Anemic Malawian Children with High Incidence of Infectious Diseases and Bone Marrow Iron Deficiency
por: Jonker, Femkje A. M., et al.
Publicado: (2013)

Menopause Delays the Typical Recovery of Pre-Exercise Hepcidin Levels after High-Intensity Interval Running Exercise in Endurance-Trained Women
por: Alfaro-Magallanes, Víctor M., et al.
Publicado: (2020)

Inverse Relationship of Serum Hepcidin Levels with CD4 Cell Counts in HIV-Infected Patients Selected from an Indonesian Prospective Cohort Study
por: Wisaksana, Rudi, et al.
Publicado: (2013)

The relationship between asymptomatic atherosclerosis and hepcidin-25 in chronic kidney disease patients
por: Mohamed, Osama Nady, et al.
Publicado: (2023)

First-in-human Phase I studies of PRS-080#22, a hepcidin antagonist, in healthy volunteers and patients with chronic kidney disease undergoing hemodialysis
por: Renders, Lutz, et al.
Publicado: (2019)

Independent Replication of Published Germline Polymorphisms Associated with Urinary Bladder Cancer Prognosis and Treatment Response
por: Grotenhuis, Anne J., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1mai05a1jm4e1r1cegumdcfocq