The prion-like RNA-processing protein HNRPDL forms inherently toxic amyloid-like inclusion bodies in bacteria

BACKGROUND: The formation of protein inclusions is connected to the onset of many human diseases. Human RNA binding proteins containing intrinsically disordered regions with an amino acid composition resembling those of yeast prion domains, like TDP-43 or FUS, are being found to aggregate in differe...

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Detalles Bibliográficos
Autores principales: Navarro, Susanna, Marinelli, Patrizia, Diaz-Caballero, Marta, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498515/
https://www.ncbi.nlm.nih.gov/pubmed/26160665
http://dx.doi.org/10.1186/s12934-015-0284-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498515/
https://www.ncbi.nlm.nih.gov/pubmed/26160665
http://dx.doi.org/10.1186/s12934-015-0284-7

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