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Accelerated Sensitivity Analysis in High-Dimensional Stochastic Reaction Networks

Existing sensitivity analysis approaches are not able to handle efficiently stochastic reaction networks with a large number of parameters and species, which are typical in the modeling and simulation of complex biochemical phenomena. In this paper, a two-step strategy for parametric sensitivity ana...

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Detalles Bibliográficos
Autores principales: Arampatzis, Georgios, Katsoulakis, Markos A., Pantazis, Yannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498611/
https://www.ncbi.nlm.nih.gov/pubmed/26161544
http://dx.doi.org/10.1371/journal.pone.0130825