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Accelerated Sensitivity Analysis in High-Dimensional Stochastic Reaction Networks
Existing sensitivity analysis approaches are not able to handle efficiently stochastic reaction networks with a large number of parameters and species, which are typical in the modeling and simulation of complex biochemical phenomena. In this paper, a two-step strategy for parametric sensitivity ana...
Autores principales: | Arampatzis, Georgios, Katsoulakis, Markos A., Pantazis, Yannis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498611/ https://www.ncbi.nlm.nih.gov/pubmed/26161544 http://dx.doi.org/10.1371/journal.pone.0130825 |
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