IRF6 Is Involved in the Regulation of Cell Proliferation and Transformation in MCF10A Cells Downstream of Notch Signaling

IRF6, a member of Interferon Regulatory Factors (IRF) family, is involved in orofacial and epidermal development. In breast cancer cell lines ectopic expression of IRF6 reduces cell numbers suggesting a role as negative regulator of cell cycle. IRF6 is a direct target of canonical Notch signaling in...

Descripción completa

Detalles Bibliográficos
Autores principales: Zengin, Talip, Ekinci, Burcu, Kucukkose, Cansu, Yalcin-Ozuysal, Ozden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498616/
https://www.ncbi.nlm.nih.gov/pubmed/26161746
http://dx.doi.org/10.1371/journal.pone.0132757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498616/
https://www.ncbi.nlm.nih.gov/pubmed/26161746
http://dx.doi.org/10.1371/journal.pone.0132757

Ejemplares similares