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IRF6 Is Involved in the Regulation of Cell Proliferation and Transformation in MCF10A Cells Downstream of Notch Signaling

IRF6, a member of Interferon Regulatory Factors (IRF) family, is involved in orofacial and epidermal development. In breast cancer cell lines ectopic expression of IRF6 reduces cell numbers suggesting a role as negative regulator of cell cycle. IRF6 is a direct target of canonical Notch signaling in...

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Detalles Bibliográficos
Autores principales:	Zengin, Talip, Ekinci, Burcu, Kucukkose, Cansu, Yalcin-Ozuysal, Ozden
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498616/ https://www.ncbi.nlm.nih.gov/pubmed/26161746 http://dx.doi.org/10.1371/journal.pone.0132757

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