Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity

Ketonic indeno[1,2-b]indole-9,10-dione derivatives, initially designed as human casein kinase II (CK2) inhibitors, were recently shown to be converted into efficient inhibitors of drug efflux by the breast cancer resistance protein ABCG2 upon suited substitutions including a N(5)-phenethyl on C-ring...

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Detalles Bibliográficos
Autores principales: Gozzi, Gustavo Jabor, Bouaziz, Zouhair, Winter, Evelyn, Daflon-Yunes, Nathalia, Honorat, Mylène, Guragossian, Nathalie, Marminon, Christelle, Valdameri, Glaucio, Bollacke, Andre, Guillon, Jean, Pinaud, Noël, Marchivie, Mathieu, Cadena, Silvia M, Jose, Joachim, Le Borgne, Marc, Di Pietro, Attilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498724/
https://www.ncbi.nlm.nih.gov/pubmed/26170632
http://dx.doi.org/10.2147/DDDT.S84982

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