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The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes

A novel biocompatible and biodegradable drug-delivery nanoparticle (NP) has been developed to minimize the severe side effects of the poorly water-soluble anticancer drug paclitaxel (PTX) for clinical use. PTX was loaded into the hydrophobic cavity of a hydrophilic cyclodextrin derivative, heptakis...

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Detalles Bibliográficos
Autores principales:	Ye, Ya-Jing, Wang, Yun, Lou, Kai-Yan, Chen, Yan-Zuo, Chen, Rongjun, Gao, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498727/ https://www.ncbi.nlm.nih.gov/pubmed/26170666 http://dx.doi.org/10.2147/IJN.S83508

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