Genome-Wide DNA Methylation Analysis Identifies Novel Hypomethylated Non-Pericentromeric Genes with Potential Clinical Implications in ICF Syndrome

INTRODUCTION AND RESULTS: Immunodeficiency, centromeric instability and facial anomalies syndrome (ICF) is a rare autosomal recessive disease, characterized by severe hypomethylation in pericentromeric regions of chromosomes (1, 16 and 9), marked immunodeficiency and facial anomalies. The majority o...

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Detalles Bibliográficos
Autores principales: Simo-Riudalbas, L., Diaz-Lagares, A., Gatto, S., Gagliardi, M., Crujeiras, A. B., Matarazzo, M. R., Esteller, M., Sandoval, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498748/
https://www.ncbi.nlm.nih.gov/pubmed/26161907
http://dx.doi.org/10.1371/journal.pone.0132517

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