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Whole-Genome Sequencing Analysis of Sapovirus Detected in South Korea
Sapovirus (SaV), a virus residing in the intestines, is one of the important causes of gastroenteritis in human beings. Human SaV genomes are classified into various genogroups and genotypes. Whole-genome analysis and phylogenetic analysis of ROK62, the SaV isolated in South Korea, were carried out....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498750/ https://www.ncbi.nlm.nih.gov/pubmed/26161646 http://dx.doi.org/10.1371/journal.pone.0132328 |
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author | Choi, Hye Lim Suh, Chang-Il Park, Seung-Won Jin, Ji-Young Cho, Han-Gil Paik, Soon-Young |
author_facet | Choi, Hye Lim Suh, Chang-Il Park, Seung-Won Jin, Ji-Young Cho, Han-Gil Paik, Soon-Young |
author_sort | Choi, Hye Lim |
collection | PubMed |
description | Sapovirus (SaV), a virus residing in the intestines, is one of the important causes of gastroenteritis in human beings. Human SaV genomes are classified into various genogroups and genotypes. Whole-genome analysis and phylogenetic analysis of ROK62, the SaV isolated in South Korea, were carried out. The ROK62 genome of 7429 nucleotides contains 3 open-reading frames (ORF). The genotype of ROK62 is SaV GI-1, and 94% of its nucleotide sequence is identical with other SaVs, namely Manchester and Mc114. Recently, SaV infection has been on the rise throughout the world, particularly in countries neighboring South Korea; however, very few academic studies have been done nationally. As the first whole-genome sequence analysis of SaV in South Korea, this research will help provide reference for the detection of recombination, tracking of epidemic spread, and development of diagnosis methods for SaV. |
format | Online Article Text |
id | pubmed-4498750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-44987502015-07-17 Whole-Genome Sequencing Analysis of Sapovirus Detected in South Korea Choi, Hye Lim Suh, Chang-Il Park, Seung-Won Jin, Ji-Young Cho, Han-Gil Paik, Soon-Young PLoS One Research Article Sapovirus (SaV), a virus residing in the intestines, is one of the important causes of gastroenteritis in human beings. Human SaV genomes are classified into various genogroups and genotypes. Whole-genome analysis and phylogenetic analysis of ROK62, the SaV isolated in South Korea, were carried out. The ROK62 genome of 7429 nucleotides contains 3 open-reading frames (ORF). The genotype of ROK62 is SaV GI-1, and 94% of its nucleotide sequence is identical with other SaVs, namely Manchester and Mc114. Recently, SaV infection has been on the rise throughout the world, particularly in countries neighboring South Korea; however, very few academic studies have been done nationally. As the first whole-genome sequence analysis of SaV in South Korea, this research will help provide reference for the detection of recombination, tracking of epidemic spread, and development of diagnosis methods for SaV. Public Library of Science 2015-07-10 /pmc/articles/PMC4498750/ /pubmed/26161646 http://dx.doi.org/10.1371/journal.pone.0132328 Text en © 2015 Choi et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Choi, Hye Lim Suh, Chang-Il Park, Seung-Won Jin, Ji-Young Cho, Han-Gil Paik, Soon-Young Whole-Genome Sequencing Analysis of Sapovirus Detected in South Korea |
title | Whole-Genome Sequencing Analysis of Sapovirus Detected in South Korea |
title_full | Whole-Genome Sequencing Analysis of Sapovirus Detected in South Korea |
title_fullStr | Whole-Genome Sequencing Analysis of Sapovirus Detected in South Korea |
title_full_unstemmed | Whole-Genome Sequencing Analysis of Sapovirus Detected in South Korea |
title_short | Whole-Genome Sequencing Analysis of Sapovirus Detected in South Korea |
title_sort | whole-genome sequencing analysis of sapovirus detected in south korea |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498750/ https://www.ncbi.nlm.nih.gov/pubmed/26161646 http://dx.doi.org/10.1371/journal.pone.0132328 |
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