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Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice

Precise understanding of radiation effects is critical to develop new modalities for the prevention and treatment of radiation-induced damage. We previously reported that non-lethal doses of X-ray irradiation induce DNA damage in human hematopoietic stem and progenitor cells (HSPCs) reconstituted in...

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Detalles Bibliográficos
Autores principales:	Wang, Changshan, Oshima, Motohiko, Sashida, Goro, Tomioka, Takahisa, Hasegawa, Nagisa, Mochizuki-Kashio, Makiko, Nakajima-Takagi, Yaeko, Kusunoki, Yoichiro, Kyoizumi, Seishi, Imai, Kazue, Nakachi, Kei, Iwama, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498777/ https://www.ncbi.nlm.nih.gov/pubmed/26161905 http://dx.doi.org/10.1371/journal.pone.0132041

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